I of course have differences with the Orthodox Church, but I found this study Bible stimulating in a positive way. I am especially intrigued by the OT section since you have here a translation of the Septuagint (Greek) text instead of the Hebrew Masoretic text as found in our standard Bibles. The differences are intriguing and the notes commonly point out such differences. These differences could be confusing to people who are unaware of such issues, but for trained pastors seeing such things can be helpful and challenging as you dialogue with another portion of the historic church.
The notes are theologically focused, thus aiming at the overall meaning of the text. Also, the notes often provide quotes from early church fathers. In this way this study Bible sometimes accomplishes in a more usable manner the goal of the Ancient Christian Commentary on Scripture Series (ed. by Tom Oden).